The stimulant nootropics are agents that promote wakefulness. As I mentioned before, I’m sure there is no person out there who didn’t reach out for a cup of coffee whenever they felt especially tired. If you are a coffee lover, you probably also have that feeling that you can’t wake up fast enough if you don’t drink it. There are many stimulants out there which would probably take me entire volumes to write about. However, I will tell you about some popular stimulants that can enhance your short-term cognitive ability. Typically, they will raise the levels of a certain group of neurotransmitters such as dopamine and adrenaline, providing you with that certain “boost of energy.”

  1. Caffeine

Caffeine is, without any doubt, one of the most powerful stimulantsthat can increase wakefulness and decrease fatigue. Although the name would make you think that you can only find it in coffee, it is also an active component in green tea leaves. Once it reaches the sensors of the brain, caffeine will start blocking the adenosine action, and thus increase the serotonin, dopamine and adrenaline levels. Many studies showed that caffeine can increase reaction time, improve exercise and cognitive performance, delay fatigue and offer an overall feeling of motivation. 

As opposed to the natural nootropics, caffeine is more prone to side effects. The USFDA recommends that beverages should contain no more than 0.02% caffeine, and the WADA has even banned its use for a period (although it was eventually removed from the list). Caffeine is toxic if it is taken in more than 400 mg per day for average adults and more than 300 mg for lactating and pregnant women. A high intake of caffeine in one go (more than 400 or 500 mg) can lead to side effects such as insomnia, irregular heartbeat, excitement, anxiety, slurred speech, irritability and muscle twitching. An even larger overdose can lead to psychosis, delusions, judgment lapses, disorientation, mania and even depression.

  1. Adderall

Adderall was defined by the FDA as a central nervous system (CNS) stimulant, and it combines neutral salts of amphetamine and dextroamphetamine with l-amphetamine aspartate monohydrate. The nootropicalso contains the destroy isomer of the amphetamine D and saccharate.

Although it is not clearly understoodwhy,Adderall can help people suffering from ADHD. It is believed that it can inhibit the uptake of dopamine (by blocking the dopamine transporter). The method of actions remains, still, elusive. It is, however, certain that Adderall can combat ADD/ADHD and enhance the impair aspects of the cognitive function. Taken at a standard dose of 10 mg every day (preferably in the morning), it can prove very useful in treating the mentioned conditions.

One needs to be aware that not all individuals can determine whether or not the Adderall makes them feel better or worse, and they all end up abusing the nootropic. Side effects from abuse can come in the form of intolerance, neurotoxicity, anxiety, irritability, mania, paranoia, insomnia, palpitations, increased blood pressure, racing heart, euphoria, appetite loss and mood changes.

  1. Bromantane

Bromantane was very popular in the 80’s in Russia. Sportsmen and soldiers could purchase it quickly back then without a prescription, which is why it was made an easily-available immuno-stimulant. It is also an anxiolytic, and it was banned from use in 1996, as part of the IOC list, after it was discovered that athletes used it several times in the Olympic Games.

Bromantane has the following actions and benefits:

  • It stimulates the nervous system by use of dopaminergic action.
  • It stimulates the serotonin receptors.
  • It increases the physical and mental work capacity.
  • It increases the memory and learning ability.
  • It reduces anxiety.
  • It has no addictive potential or withdrawal symptoms.
  • It barely has any side effects.

The dosage of bromantane seems to be sex-dependent. If you were like me and assumed that the “bro” makes it more of a men stimulant, then you were as wrong as I was. The bromantaneis absorbed significantly faster by women, and if men would feel the effects in 4 hours, women would feel it in 2.75.

The correct dose of bromantane is 300mg per kg, and that is when it acts as a stimulant. If, however, you administer very high levels of bromantane to make yourself more alert, you may end up feeling sleepier instead. A toxic dose of 600 mg per kg will have a sedative effect. Other than that, there are no known side effects to bromantane.

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